Evaluation of Antiperspirant Agents Effect on the Size of Axillary Lymph Nodes in Iranian Women

Introduction: Size of axillary lymph nodes can be a predictor for breast abnormalities. The agents in the antiperspirants such as Aluminum were observed in the breast biopsy of individual with abnormalities and antiperspirants usage. In this study, the relation between using antiperspirants and the size of axillary lymph nodes were evaluated in Iranian women. Methods: In this study, 120 women were enrolled and asked for using the antiperspirant agents. Then ultrasound and mammography were taken from these cases and axillary lymph nodes were measured in both sides. Then, the sizes were compared in the cases with regular use of antiperspirants and without use of these agents. Results: In the present study, 120 normal women were studied. Mean age of sample group was 38.02 and all samples were female. Seventy eight cases (65%) used antiperspirant agents as usual and 42 cases (35%) did not. There were no significant differences between age, right and left nodes size of the cases with and without the use of antiperspirant agents (P≤0.05). Conclusion: The results confirmed that size index is not a sufficient factor for malignancy and using antiperspirant wasn’t producing abnormal statue in axillary lymph nodes and node with large size wasn’t from lymphadenopathy or malignancy in Iranian women.